Meglumine antimoniate

Meglumine antimoniate

Systematic (IUPAC) name
Hydroxy-dioxostiborane; (2R,3R,4R,5S)-6-methylaminohexane-1,2,3,4,5-pentol
Clinical data
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	133-51-7^N
ATC code	P01CB01 QP51AB01
PubChem	CID 64953
ChemSpider	58479^Y
ChEMBL	CHEMBL239129^Y
Chemical data
Formula	Variable
Mol. mass	Variable
SMILES	eMolecules & PubChem
InChI InChI=1S/C7H17NO5.H2O.2O.Sb/c1-8-2-4(10)6(12)7(13)5(11)3-9;;;;/h4-13H,2-3H2,1H3;1H2;;;/q;;;;+1/p-1/t4-,5+,6+,7+;;;;/m0..../s1^Y Key:XOGYVDXPYVPAAQ-SESJOKTNSA-M^Y
N(what is this?) (verify)

Meglumine antimoniate (or meglumine antimonate) is a medicine used for treating leishmaniasis. It is manufactured by Aventis and sold as Glucantime in France, and Glucantim in Italy. It belongs to a group of compounds known as the pentavalent antimonials. It is administered by intramuscular injection.

Trypanosomiasis	African trypanosomiasis: ornithine (Eflornithine^#) • arsenical (Melarsoprol^#) • benzamidine (Pentamidine^#) • naphthalenesulfonate (Suramin^#) Chagas disease: nitroimidazole (Benznidazole^#) • nitrofuran (Nifurtimox^#)

Leishmaniasis	macrolide (Amphotericin B^#) Pentavalent antimonials (Meglumine antimoniate^#, Sodium stibogluconate) benzamidine (Pentamidine^#) • phosphorylcholine (Miltefosine) • neomycin (Paromomycin)

PAM	macrolide (Amphotericin B)

Trichozoa

Giardiasis	nitroimidazole (Metronidazole^#, Tinidazole) • benzimidazole (Albendazole) thiazole (Nitazoxanide) • nitrofuran (Furazolidone) aminoacridine (Quinacrine)

Trichomoniasis	nitroimidazole (Metronidazole^#, Tinidazole)

Dientamoebiasis	nitroimidazole (Metronidazole, Secnidazole) oxyquinoline (Iodoquinol) • tetracycline (Doxycycline) • neomycin (Paromomycin)

^#WHO-EM. ^‡Withdrawn from market. Clinical trials: ^†Phase III. ^§Never to phase III

M: PRO

ambz, excv, chrm (strc)

ambz, excv, chrm

Meglumine antimoniate

See also